ceesdekker.net for Dummies
ceesdekker.net for Dummies
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Nanotechnology delivers A selection of alternatives to add to biology. Here I will present examples wherever nanofabrication – a chance to make confined buildings with Proportions at will – is used to examine the biophysics of one molecules and cells. I will present some illustrations from our lab:
Our group research bacterial cell division which is aiming to represent a ‘base up biology’ in synthetic cells which will autonomously divide. Our primary interest lies in cell division, chromatin construction, and spatial Handle.
For a individual, I possess the biblical assignment to check out and use everything in creation for the advantage of my neighbour. I never encounter any conflict between faith and science. On the contrary, my faith stimulates me to try and do science, to be open-minded on earth.’
I'm able to hardly envision how I, as a geneticist, would have the ability to discover fundamental physics, not to mention contend at the very best. How did you go about it?
De sterke polarisatie in de discussie rond schepping/evolutie en meer algemeen rond geloof/wetenschap lijkt helaas geen eind te kennen. Toch is er wel degelijk een heilzame middenweg, maar deze krijgt in excess of het algemeen weinig aandacht. Dit boek kan hier wellicht verandering in brengen. Wie de geschiedenis van de relatie tussen geloof en wetenschap in duikt, komt tot verrassende inzichten. De moderne mens leeft satisfied veel stereotypen die historisch niet verantwoord blijken te zijn. Afgezaagde typeringen als ‘Vroeger dachten we dat de
Instance (3) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim from the pore is highlighted in red, in addition to a 3D rendering with the movement from the DNA rod is exhibited.
Considering that 2000 he moved to single-molecule biophysics and nanobiology, with research from DNA supercoiling studies of nucleosomes and DNA maintenance proteins to DNA translocation by nanopores. Just lately his study has centered on finding out cell division with microbes on chip, even though his final interest is from the course of acknowledging synthetic cells.
2000, discovery that nanotubes can have extraordinary massive current densities; settled the controversial challenge of electronic transport by DNA molecules by measurements of insulating behavior at The only molecule stage; and demonstration of the AFM method for solitary-molecule manipulation of nanotubes
‘You should not just think of the questions of tomorrow, but in addition take into account the inquiries of your working day immediately after tomorrow’
Dekker started out his study on one carbon nanotubes in 1993 when he build a fresh line of study to check electrical transport through solitary natural molecules between nanoelectrodes. In 1996 a breakthrough was recognized with carbon nanotubes. This was attained in a collaboration Along with the group of Nobel laureate Richard Smalley. STM and nanolithography techniques have been used to display that these nanotubes are quantum wires at the single-molecule stage, with fantastic physical Houses.
In 1993 he was appointed as Associate Professor at Delft University of Technological know-how. Inside the mid-nineties Dekker and his workforce attained results with the invention from the electronic Houses of carbon nanotubes, the first single-molecule transistor together with other nanoscience.
‘That concerns the synthetic mobile, as A part of the Dutch BaSyC initiative. Craig Venter seemed top-down in People times and identified about five hundred genes which have been minimally needed for your functioning cell. We wish to look bottom-up: how can we shift from a handful of molecules to an entire Organic method?
Let’s very first seem back again at this time when you decided to shift your focus from superconductivity and nanotubes to ceesdekker.net biology at the end of the 1990s.
2004, discovery of new physics in translocation of DNA through nanopores; initially experimental research of ions conduction in nanofluidic channels; first electrochemistry with particular person single-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; very first electrical docking of microtubules on kinesin-coated nanostructures; first biophysics characterization with the mechanical Qualities of double-stranded RNA; and to start with solitary-molecule study of DNA translocation by a restriction-modification enzyme.